Digital PCR can provide improved BCR-ABL1 detection in chronic myeloid leukemia patients in deep molecular response and sensitivity of standard quantitative methods using EAC assays

BCR-ABL1 molecular detection using quantitative PCR (qPCR) methods is the golden standard of chronic myeloid leukemia (CML) monitoring. However, due to variable sensitivity of qPCR assays across laboratories, alternative methods are tested. Digital PCR (dPCR) has been suggested as a robust and repro...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pract Lab Med
Main Authors: Smitalova, Dagmar, Dvorakova, Dana, Racil, Zdenek, Romzova, Marianna
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Short Communication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985703/
https://ncbi.nlm.nih.gov/pubmed/33778144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plabm.2021.e00210
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