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Digital PCR can provide improved BCR-ABL1 detection in chronic myeloid leukemia patients in deep molecular response and sensitivity of standard quantitative methods using EAC assays

BCR-ABL1 molecular detection using quantitative PCR (qPCR) methods is the golden standard of chronic myeloid leukemia (CML) monitoring. However, due to variable sensitivity of qPCR assays across laboratories, alternative methods are tested. Digital PCR (dPCR) has been suggested as a robust and repro...

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Detalhes bibliográficos
Publicado no:Pract Lab Med
Main Authors: Smitalova, Dagmar, Dvorakova, Dana, Racil, Zdenek, Romzova, Marianna
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985703/
https://ncbi.nlm.nih.gov/pubmed/33778144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plabm.2021.e00210
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