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A Potential Mechanism Underlying the Therapeutic Effects of Progesterone and Allopregnanolone on Ketamine-Induced Cognitive Deficits

Ketamine exposure can model cognitive deficits associated with schizophrenia. Progesterone (PROG) and its active metabolite allopregnanolone (ALLO) have neuroprotective effects and the pathway involving progesterone receptor membrane component 1 (PGRMC1), epidermal growth factor receptor (EGFR), glu...

詳細記述

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書誌詳細
出版年:Front Pharmacol
主要な著者: Cao, Ting, Tang, MiMi, Jiang, Pei, Zhang, BiKui, Wu, XiangXin, Chen, Qian, Zeng, CuiRong, Li, NaNa, Zhang, ShuangYang, Cai, HuaLin
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985688/
https://ncbi.nlm.nih.gov/pubmed/33767621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.612083
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