A Potential Mechanism Underlying the Therapeutic Effects of Progesterone and Allopregnanolone on Ketamine-Induced Cognitive Deficits

Ketamine exposure can model cognitive deficits associated with schizophrenia. Progesterone (PROG) and its active metabolite allopregnanolone (ALLO) have neuroprotective effects and the pathway involving progesterone receptor membrane component 1 (PGRMC1), epidermal growth factor receptor (EGFR), glu...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Cao, Ting, Tang, MiMi, Jiang, Pei, Zhang, BiKui, Wu, XiangXin, Chen, Qian, Zeng, CuiRong, Li, NaNa, Zhang, ShuangYang, Cai, HuaLin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985688/
https://ncbi.nlm.nih.gov/pubmed/33767621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.612083
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