The Allopregnanolone to Progesterone Ratio Across the Menstrual Cycle and in Menopause

The neuroactive steroid 3α-5α-tetrahydroprogesterone (allopregnanolone), a metabolite of progesterone, is a positive allosteric modulator of GABA(A) receptors, and low levels have been implicated in the etiology of mood disorders. However, it is not known whether metabolism of progesterone to allopr...

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Udgivet i:Psychoneuroendocrinology
Main Authors: Kimball, Allison, Dichtel, Laura E., Nyer, Maren B., Mischoulon, David, Fisher, Lauren B., Cusin, Cristina, Dording, Christina M., Trinh, Nhi-Ha, Yeung, Albert, Haines, Melanie S., Sung, Joshua C., Pinna, Graziano, Rasmusson, Ann M., Carpenter, Linda L., Fava, Maurizio, Klibanski, Anne, Miller, Karen Klahr
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935417/
https://ncbi.nlm.nih.gov/pubmed/31780185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2019.104512
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