A Potential Mechanism Underlying the Therapeutic Effects of Progesterone and Allopregnanolone on Ketamine-Induced Cognitive Deficits

Ketamine exposure can model cognitive deficits associated with schizophrenia. Progesterone (PROG) and its active metabolite allopregnanolone (ALLO) have neuroprotective effects and the pathway involving progesterone receptor membrane component 1 (PGRMC1), epidermal growth factor receptor (EGFR), glu...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Cao, Ting, Tang, MiMi, Jiang, Pei, Zhang, BiKui, Wu, XiangXin, Chen, Qian, Zeng, CuiRong, Li, NaNa, Zhang, ShuangYang, Cai, HuaLin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985688/
https://ncbi.nlm.nih.gov/pubmed/33767621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.612083
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