Llwytho...
Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro
The amyloid precursor protein (APP) is a transmembrane protein mostly found in neurons. Cleavage of this protein by β-secretase can lead to the formation of amyloid-β (Aβ) peptide plaque, which leads to Alzheimer’s disease. Genomic analysis of an Icelandic population that did not show symptoms of Al...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Mol Ther Nucleic Acids |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society of Gene & Cell Therapy
2021
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7985668/ https://ncbi.nlm.nih.gov/pubmed/33815938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.02.032 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|