Immunogenicity Risk Profile of Nanobodies

Nanobodies (Nbs), the variable domains of camelid heavy chain-only antibodies, are a promising class of therapeutics or in vivo imaging reagents entering the clinic. They possess unique characteristics, including a minimal size, providing fast pharmacokinetics, high-target specificity, and an affini...

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Publicado en:Front Immunol
Autores principales: Ackaert, Chloé, Smiejkowska, Natalia, Xavier, Catarina, Sterckx, Yann G. J., Denies, Sofie, Stijlemans, Benoit, Elkrim, Yvon, Devoogdt, Nick, Caveliers, Vicky, Lahoutte, Tony, Muyldermans, Serge, Breckpot, Karine, Keyaerts, Marleen
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985456/
https://ncbi.nlm.nih.gov/pubmed/33767701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.632687
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