Targeted alpha therapy using short-lived alpha-particles and the promise of nanobodies as targeting vehicle

Introduction: The combination of a targeted biomolecule that specifically defines the target and a radionuclide that delivers a cytotoxic payload offers a specific way to destroy cancer cells. Targeted radionuclide therapy (TRNT) aims to deliver cytotoxic radiation to cancer cells and causes minimal...

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Dettagli Bibliografici
Pubblicato in:Expert Opin Biol Ther
Autori principali: Dekempeneer, Yana, Keyaerts, Marleen, Krasniqi, Ahmet, Puttemans, Janik, Muyldermans, Serge, Lahoutte, Tony, D’huyvetter, Matthias, Devoogdt, Nick
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940885/
https://ncbi.nlm.nih.gov/pubmed/27145158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14712598.2016.1185412
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