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Targeted Radionuclide Therapy with A (177)Lu-labeled Anti-HER2 Nanobody

RIT has become an attractive strategy in cancer treatment, but still faces important drawbacks due to poor tumor penetration and undesirable pharmacokinetics of the targeting vehicles. Smaller radiolabeled antibody fragments and peptides feature highly specific target accumulation, resulting in low...

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Detalhes bibliográficos
Main Authors: D'Huyvetter, Matthias, Vincke, Cécile, Xavier, Catarina, Aerts, An, Impens, Nathalie, Baatout, Sarah, De Raeve, Hendrik, Muyldermans, Serge, Caveliers, Vicky, Devoogdt, Nick, Lahoutte, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038753/
https://ncbi.nlm.nih.gov/pubmed/24883121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.8156
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