Targeted Radionuclide Therapy with A (177)Lu-labeled Anti-HER2 Nanobody

RIT has become an attractive strategy in cancer treatment, but still faces important drawbacks due to poor tumor penetration and undesirable pharmacokinetics of the targeting vehicles. Smaller radiolabeled antibody fragments and peptides feature highly specific target accumulation, resulting in low...

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Bibliographische Detailangaben
Hauptverfasser: D'Huyvetter, Matthias, Vincke, Cécile, Xavier, Catarina, Aerts, An, Impens, Nathalie, Baatout, Sarah, De Raeve, Hendrik, Muyldermans, Serge, Caveliers, Vicky, Devoogdt, Nick, Lahoutte, Tony
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038753/
https://ncbi.nlm.nih.gov/pubmed/24883121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.8156
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