Immunogenicity Risk Profile of Nanobodies

Nanobodies (Nbs), the variable domains of camelid heavy chain-only antibodies, are a promising class of therapeutics or in vivo imaging reagents entering the clinic. They possess unique characteristics, including a minimal size, providing fast pharmacokinetics, high-target specificity, and an affini...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Ackaert, Chloé, Smiejkowska, Natalia, Xavier, Catarina, Sterckx, Yann G. J., Denies, Sofie, Stijlemans, Benoit, Elkrim, Yvon, Devoogdt, Nick, Caveliers, Vicky, Lahoutte, Tony, Muyldermans, Serge, Breckpot, Karine, Keyaerts, Marleen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985456/
https://ncbi.nlm.nih.gov/pubmed/33767701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.632687
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