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The Perils of Navigating Activity-Dependent Alternative Splicing of Neurexins

Neurexins are presynaptic cell-adhesion molecules essential for synaptic function that are expressed in thousands of alternatively spliced isoforms. Recent studies suggested that alternative splicing at splice site 4 (SS4) of Nrxn1 is tightly regulated by an activity-dependent mechanism. Given that...

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Foilsithe in:Front Mol Neurosci
Main Authors: Liakath-Ali, Kif, Südhof, Thomas C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985251/
https://ncbi.nlm.nih.gov/pubmed/33767611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.659681
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