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Structures of neurexophilin–neurexin complexes reveal a regulatory mechanism of alternative splicing

Neurexins are presynaptic, cell‐adhesion molecules that specify the functional properties of synapses via interactions with trans‐synaptic ligands. Neurexins are extensively alternatively spliced at six canonical sites that regulate multifarious ligand interactions, but the structural mechanisms und...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Wilson, Steven C, White, K Ian, Zhou, Qiangjun, Pfuetzner, Richard A, Choi, Ucheor B, Südhof, Thomas C, Brunger, Axel T
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856630/
https://ncbi.nlm.nih.gov/pubmed/31566781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019101603
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