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Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA- and AMPA-Receptor Responses

AMPA- and NMDA-type glutamate receptors mediate distinct postsynaptic signals that differ characteristically among synapses. How postsynaptic AMPA- and NMDA-receptor levels are regulated, however, remains unclear. Using newly generated conditional knockin mice that enable genetic control of neurexin...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Dai, Jinye, Aoto, Jason, Sudhof, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554035/
https://ncbi.nlm.nih.gov/pubmed/31005376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.03.032
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