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Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing

Neurexins are evolutionarily conserved presynaptic cell-adhesion molecules that are essential for normal synapse formation and synaptic transmission. Indirect evidence has indicated that extensive alternative splicing of neurexin mRNAs may produce hundreds if not thousands of neurexin isoforms, but...

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Autors principals: Treutlein, Barbara, Gokce, Ozgun, Quake, Stephen R., Südhof, Thomas C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977267/
https://ncbi.nlm.nih.gov/pubmed/24639501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403244111
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