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Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing

Neurexins are evolutionarily conserved presynaptic cell-adhesion molecules that are essential for normal synapse formation and synaptic transmission. Indirect evidence has indicated that extensive alternative splicing of neurexin mRNAs may produce hundreds if not thousands of neurexin isoforms, but...

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Detalhes bibliográficos
Main Authors: Treutlein, Barbara, Gokce, Ozgun, Quake, Stephen R., Südhof, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977267/
https://ncbi.nlm.nih.gov/pubmed/24639501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403244111
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