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Membrane-Tethered Monomeric Neurexin LNS-Domain Triggers Synapse Formation

Neurexins are presynaptic cell-adhesion molecules that bind to postsynaptic cell-adhesion molecules such as neuroligins and leucine-rich repeat transmembrane proteins (LRRTMs). When neuroligins or LRRTMs are expressed in a nonneuronal cell, cocultured neurons avidly form heterologous synapses onto t...

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Bibliografiske detaljer
Main Authors: Gokce, Ozgun, Südhof, Thomas C.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761060/
https://ncbi.nlm.nih.gov/pubmed/24005312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1232-13.2013
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