Triptolide Induces Leydig Cell Apoptosis by Disrupting Mitochondrial Dynamics in Rats

Triptolide is widely used in the clinical treatment of various diseases. Side effects, including reproductive toxicity to male patients, limit its application. However, no detailed mechanisms or potential intervention targets have been reported. In this study, we show that triptolide activated the m...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Lv, Linyan, Chang, Yajie, Li, Yanqing, Chen, Haicheng, Yao, Jiahui, Xie, Yun, Liang, Xiaoyan, Yang, Xing, Zhang, Min, Liu, Guihua
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985071/
https://ncbi.nlm.nih.gov/pubmed/33767625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.616803
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