FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice

Male late-onset hypogonadism is an age-related disease, the core mechanism of which is dysfunction of senescent Leydig cells. Recent studies have shown that elimination of senescent cells can restore proper homeostasis to aging tissue. In the present study, we found that the fork head box O (FOXO) t...

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Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Autores principales: Zhang, Chi, Xie, Yun, Chen, Haicheng, Lv, Linyan, Yao, Jiahui, Zhang, Min, Xia, Kai, Feng, Xin, Li, Yanqing, Liang, Xiaoyan, Sun, Xiangzhou, Deng, Chunhua, Liu, Guihua
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053614/
https://ncbi.nlm.nih.gov/pubmed/31959736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102682
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