Triptolide Induces Leydig Cell Apoptosis by Disrupting Mitochondrial Dynamics in Rats

Triptolide is widely used in the clinical treatment of various diseases. Side effects, including reproductive toxicity to male patients, limit its application. However, no detailed mechanisms or potential intervention targets have been reported. In this study, we show that triptolide activated the m...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lv, Linyan, Chang, Yajie, Li, Yanqing, Chen, Haicheng, Yao, Jiahui, Xie, Yun, Liang, Xiaoyan, Yang, Xing, Zhang, Min, Liu, Guihua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985071/
https://ncbi.nlm.nih.gov/pubmed/33767625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.616803
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