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Triptolide Induces Leydig Cell Apoptosis by Disrupting Mitochondrial Dynamics in Rats

Triptolide is widely used in the clinical treatment of various diseases. Side effects, including reproductive toxicity to male patients, limit its application. However, no detailed mechanisms or potential intervention targets have been reported. In this study, we show that triptolide activated the m...

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Опубликовано в: :Front Pharmacol
Главные авторы: Lv, Linyan, Chang, Yajie, Li, Yanqing, Chen, Haicheng, Yao, Jiahui, Xie, Yun, Liang, Xiaoyan, Yang, Xing, Zhang, Min, Liu, Guihua
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985071/
https://ncbi.nlm.nih.gov/pubmed/33767625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.616803
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