Triptolide Induces Leydig Cell Apoptosis by Disrupting Mitochondrial Dynamics in Rats

Triptolide is widely used in the clinical treatment of various diseases. Side effects, including reproductive toxicity to male patients, limit its application. However, no detailed mechanisms or potential intervention targets have been reported. In this study, we show that triptolide activated the m...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Lv, Linyan, Chang, Yajie, Li, Yanqing, Chen, Haicheng, Yao, Jiahui, Xie, Yun, Liang, Xiaoyan, Yang, Xing, Zhang, Min, Liu, Guihua
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985071/
https://ncbi.nlm.nih.gov/pubmed/33767625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.616803
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