FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice

Male late-onset hypogonadism is an age-related disease, the core mechanism of which is dysfunction of senescent Leydig cells. Recent studies have shown that elimination of senescent cells can restore proper homeostasis to aging tissue. In the present study, we found that the fork head box O (FOXO) t...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhang, Chi, Xie, Yun, Chen, Haicheng, Lv, Linyan, Yao, Jiahui, Zhang, Min, Xia, Kai, Feng, Xin, Li, Yanqing, Liang, Xiaoyan, Sun, Xiangzhou, Deng, Chunhua, Liu, Guihua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053614/
https://ncbi.nlm.nih.gov/pubmed/31959736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102682
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