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Fusion partners of NTRK3 affect subcellular localization of the fusion kinase and cytomorphology of melanocytes

A subset of Spitz tumors harbor fusions of NTRK3 with ETV6, MYO5A, and MYH9. We evaluated a series of 22 melanocytic tumors in which an NTRK3 fusion was identified as part of the diagnostic workup. Tumors in which NTRK3 was fused to ETV6 occurred in younger patients, were predominantly composed of e...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: de la Fouchardière, Arnaud, Tee, Meng Kian, Peternel, Sandra, Valdebran, Manuel, Pissaloux, Daniel, Tirode, Franck, Busam, Klaus J., LeBoit, Philip E., McCalmont, Timothy H., Bastian, Boris C., Yeh, Iwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985048/
https://ncbi.nlm.nih.gov/pubmed/32968185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-020-00678-6
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