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Cerebellar developmental deficits underlie neurodegenerative disorder spinocerebellar ataxia type 23

Spinocerebellar ataxia type 23 (SCA23) is a late‐onset neurodegenerative disorder characterized by slowly progressive gait and limb ataxia, for which there is no therapy available. It is caused by pathogenic variants in PDYN, which encodes prodynorphin (PDYN). PDYN is processed into the opioid pepti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Brain Pathol
Prif Awduron: Smeets, Cleo J.L.M., Ma, Kai Yu, Fisher, Simon E., Verbeek, Dineke S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983976/
https://ncbi.nlm.nih.gov/pubmed/33043513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12905
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