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Cerebellar developmental deficits underlie neurodegenerative disorder spinocerebellar ataxia type 23

Spinocerebellar ataxia type 23 (SCA23) is a late‐onset neurodegenerative disorder characterized by slowly progressive gait and limb ataxia, for which there is no therapy available. It is caused by pathogenic variants in PDYN, which encodes prodynorphin (PDYN). PDYN is processed into the opioid pepti...

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Dades bibliogràfiques
Publicat a:Brain Pathol
Autors principals: Smeets, Cleo J.L.M., Ma, Kai Yu, Fisher, Simon E., Verbeek, Dineke S.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983976/
https://ncbi.nlm.nih.gov/pubmed/33043513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12905
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