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Cerebellar developmental deficits underlie neurodegenerative disorder spinocerebellar ataxia type 23
Spinocerebellar ataxia type 23 (SCA23) is a late‐onset neurodegenerative disorder characterized by slowly progressive gait and limb ataxia, for which there is no therapy available. It is caused by pathogenic variants in PDYN, which encodes prodynorphin (PDYN). PDYN is processed into the opioid pepti...
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| Publicado no: | Brain Pathol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7983976/ https://ncbi.nlm.nih.gov/pubmed/33043513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12905 |
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