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Cerebellar developmental deficits underlie neurodegenerative disorder spinocerebellar ataxia type 23
Spinocerebellar ataxia type 23 (SCA23) is a late‐onset neurodegenerative disorder characterized by slowly progressive gait and limb ataxia, for which there is no therapy available. It is caused by pathogenic variants in PDYN, which encodes prodynorphin (PDYN). PDYN is processed into the opioid pepti...
Gespeichert in:
| Veröffentlicht in: | Brain Pathol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7983976/ https://ncbi.nlm.nih.gov/pubmed/33043513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12905 |
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