Hedgehog signaling in endocrine and folliculo-stellate cells of the adult pituitary

Ubiquitous overactivation of Hedgehog signaling in adult pituitaries results in increased expression of proopiomelanocortin (Pomc), growth hormone (Gh) and prolactin (Prl), elevated adrenocorticotropic hormone (Acth) production and proliferation of Sox2(+) cells. Moreover, ACTH, GH and PRL-expressin...

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Dades bibliogràfiques
Publicat a:J Endocrinol
Autors principals: Botermann, Dominik Simon, Brandes, Nadine, Frommhold, Anke, Heß, Ina, Wolff, Alexander, Zibat, Arne, Hahn, Heidi, Buslei, Rolf, Uhmann, Anja
Format: Artigo
Idioma:Inglês
Publicat: Bioscientifica Ltd 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983331/
https://ncbi.nlm.nih.gov/pubmed/33480359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-20-0388
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