Hedgehog signaling in endocrine and folliculo-stellate cells of the adult pituitary

Ubiquitous overactivation of Hedgehog signaling in adult pituitaries results in increased expression of proopiomelanocortin (Pomc), growth hormone (Gh) and prolactin (Prl), elevated adrenocorticotropic hormone (Acth) production and proliferation of Sox2(+) cells. Moreover, ACTH, GH and PRL-expressin...

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Detalles Bibliográficos
Publicado en:J Endocrinol
Main Authors: Botermann, Dominik Simon, Brandes, Nadine, Frommhold, Anke, Heß, Ina, Wolff, Alexander, Zibat, Arne, Hahn, Heidi, Buslei, Rolf, Uhmann, Anja
Formato: Artigo
Idioma:Inglês
Publicado: Bioscientifica Ltd 2021
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983331/
https://ncbi.nlm.nih.gov/pubmed/33480359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-20-0388
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