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Hedgehog signaling in endocrine and folliculo-stellate cells of the adult pituitary

Ubiquitous overactivation of Hedgehog signaling in adult pituitaries results in increased expression of proopiomelanocortin (Pomc), growth hormone (Gh) and prolactin (Prl), elevated adrenocorticotropic hormone (Acth) production and proliferation of Sox2(+) cells. Moreover, ACTH, GH and PRL-expressin...

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Bibliografische gegevens
Gepubliceerd in:J Endocrinol
Hoofdauteurs: Botermann, Dominik Simon, Brandes, Nadine, Frommhold, Anke, Heß, Ina, Wolff, Alexander, Zibat, Arne, Hahn, Heidi, Buslei, Rolf, Uhmann, Anja
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Bioscientifica Ltd 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983331/
https://ncbi.nlm.nih.gov/pubmed/33480359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-20-0388
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