Hedgehog signaling in endocrine and folliculo-stellate cells of the adult pituitary

Ubiquitous overactivation of Hedgehog signaling in adult pituitaries results in increased expression of proopiomelanocortin (Pomc), growth hormone (Gh) and prolactin (Prl), elevated adrenocorticotropic hormone (Acth) production and proliferation of Sox2(+) cells. Moreover, ACTH, GH and PRL-expressin...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Endocrinol
Main Authors: Botermann, Dominik Simon, Brandes, Nadine, Frommhold, Anke, Heß, Ina, Wolff, Alexander, Zibat, Arne, Hahn, Heidi, Buslei, Rolf, Uhmann, Anja
Format: Artigo
Jezik:Inglês
Izdano: Bioscientifica Ltd 2021
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983331/
https://ncbi.nlm.nih.gov/pubmed/33480359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-20-0388
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