Plasma and cerebrospinal fluid pharmacokinetics of select chemotherapeutic agents following intranasal delivery in a non-human primate model

The blood–brain barrier (BBB) limits entry of most chemotherapeutic agents into the CNS, resulting in inadequate exposure within CNS tumor tissue. Intranasal administration is a proposed means of delivery that can bypass the BBB, potentially resulting in more effective chemotherapeutic exposure at t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: League-Pascual, James C., Lester-McCully, Cynthia M., Shandilya, Shaefali, Ronner, Lukas, Rodgers, Louis, Cruz, Rafael, Peer, Cody J., Figg, William D., Warren, Katherine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7983166/
https://ncbi.nlm.nih.gov/pubmed/28290002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-017-2388-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados