Conditional Silencing of H-2D(b) Class I Molecule Expression Modulates the Protective and Pathogenic Kinetics of Virus-Antigen–Specific CD8 T Cell Responses during Theiler’s Virus Infection

Theiler’s murine encephalomyelitis virus (TMEV) infection of the CNS is cleared in C57BL/6 mice by a CD8 T cell response restricted by the MHC class I molecule H-2D(b). The identity and function of the APC(s) involved in the priming of this T cell response is (are) poorly defined. To address this ga...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Immunol
मुख्य लेखकों: Tritz, Zachariah P., Orozco, Robin C., Malo, Courtney S., Ayasoufi, Katayoun, Fain, Cori E., Khadka, Roman H., Goddery, Emma N., Yokanovich, Lila T., Settell, Megan L., Hansen, Michael J., Jin, Fang, Pavelko, Kevin D., Pease, Larry R., Johnson, Aaron J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981782/
https://ncbi.nlm.nih.gov/pubmed/32737149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000340
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