Conditional Silencing of H-2D(b) Class I Molecule Expression Modulates the Protective and Pathogenic Kinetics of Virus-Antigen–Specific CD8 T Cell Responses during Theiler’s Virus Infection

Theiler’s murine encephalomyelitis virus (TMEV) infection of the CNS is cleared in C57BL/6 mice by a CD8 T cell response restricted by the MHC class I molecule H-2D(b). The identity and function of the APC(s) involved in the priming of this T cell response is (are) poorly defined. To address this ga...

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Publicado no:J Immunol
Main Authors: Tritz, Zachariah P., Orozco, Robin C., Malo, Courtney S., Ayasoufi, Katayoun, Fain, Cori E., Khadka, Roman H., Goddery, Emma N., Yokanovich, Lila T., Settell, Megan L., Hansen, Michael J., Jin, Fang, Pavelko, Kevin D., Pease, Larry R., Johnson, Aaron J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981782/
https://ncbi.nlm.nih.gov/pubmed/32737149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000340
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