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IMMU-25. SEVERE AND MULTIFACETED SYSTEMIC IMMUNOSUPPRESSION CAUSED BY EXPERIMENTAL CANCERS OF THE CENTRAL NERVOUS SYSTEM REQUIRES RELEASE OF NON-STEROID SOLUBLE MEDIATORS

Immunosuppression of unknown etiology is a hallmark feature of glioblastoma (GBM) and is characterized by decreased CD4 T cell counts and down regulation of MHC class II expression on peripheral blood monocytes in patients. This immunosuppression is a critical barrier to the successful development o...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Ayasoufi, Katayoun, Pfaller, Christian, Evgin, Laura, Khadka, Roman, Tritz, Zachariah, Goddery, Emma, Fain, Cori, Yokanovich, Lila, Himes, Benjamin, Jin, Fang, Zheng, Jiaying, Schuelke, Matthew, Hansen, Michael, Tung, Wesley, Parney, Ian, Pease, Latty, Vile, Richard, Johnson, Aaron
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650917/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.455
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