Brain cancer induces systemic immunosuppression through release of non-steroid soluble mediators

Immunosuppression of unknown aetiology is a hallmark feature of glioblastoma and is characterized by decreased CD4 T-cell counts and downregulation of major histocompatibility complex class II expression on peripheral blood monocytes in patients. This immunosuppression is a critical barrier to the s...

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Dettagli Bibliografici
Pubblicato in:Brain
Autori principali: Ayasoufi, Katayoun, Pfaller, Christian K, Evgin, Laura, Khadka, Roman H, Tritz, Zachariah P, Goddery, Emma N, Fain, Cori E, Yokanovich, Lila T, Himes, Benjamin T, Jin, Fang, Zheng, Jiaying, Schuelke, Matthew R, Hansen, Michael J, Tung, Wesley, Parney, Ian F, Pease, Larry R, Vile, Richard G, Johnson, Aaron J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954397/
https://ncbi.nlm.nih.gov/pubmed/33253355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa343
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