DNMT1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondrial dynamics

White adipose tissue (WAT) is a key regulator of systemic energy metabolism, and impaired WAT plasticity characterized by enlargement of preexisting adipocytes associates with WAT dysfunction, obesity, and metabolic complications. However, the mechanisms that retain proper adipose tissue plasticity...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Park, Yoon Jeong, Lee, Sangseon, Lim, Sangsoo, Nahmgoong, Hahn, Ji, Yul, Huh, Jin Young, Alfadda, Assim A., Kim, Sun, Kim, Jae Bum
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980432/
https://ncbi.nlm.nih.gov/pubmed/33836591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021073118
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