DNMT1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondrial dynamics

White adipose tissue (WAT) is a key regulator of systemic energy metabolism, and impaired WAT plasticity characterized by enlargement of preexisting adipocytes associates with WAT dysfunction, obesity, and metabolic complications. However, the mechanisms that retain proper adipose tissue plasticity...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Park, Yoon Jeong, Lee, Sangseon, Lim, Sangsoo, Nahmgoong, Hahn, Ji, Yul, Huh, Jin Young, Alfadda, Assim A., Kim, Sun, Kim, Jae Bum
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2021
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980432/
https://ncbi.nlm.nih.gov/pubmed/33836591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021073118
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