DNMT1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondrial dynamics

White adipose tissue (WAT) is a key regulator of systemic energy metabolism, and impaired WAT plasticity characterized by enlargement of preexisting adipocytes associates with WAT dysfunction, obesity, and metabolic complications. However, the mechanisms that retain proper adipose tissue plasticity...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Park, Yoon Jeong, Lee, Sangseon, Lim, Sangsoo, Nahmgoong, Hahn, Ji, Yul, Huh, Jin Young, Alfadda, Assim A., Kim, Sun, Kim, Jae Bum
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2021
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980432/
https://ncbi.nlm.nih.gov/pubmed/33836591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021073118
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