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Safeguarding parental identity: Dnmt1 maintains imprints during epigenetic reprogramming in early embryogenesis
During early mammalian embryogenesis, the genome undergoes global epigenetic reprogramming, losing most of its methylation before re-establishing it de novo at implantation. However, faithful maintenance of methylation at imprinted genes during this process is vital for embryonic development, but th...
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| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Cold Spring Harbor Laboratory Press
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732418/ https://ncbi.nlm.nih.gov/pubmed/18559472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1690508 |
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