DNMT1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondrial dynamics

White adipose tissue (WAT) is a key regulator of systemic energy metabolism, and impaired WAT plasticity characterized by enlargement of preexisting adipocytes associates with WAT dysfunction, obesity, and metabolic complications. However, the mechanisms that retain proper adipose tissue plasticity...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Park, Yoon Jeong, Lee, Sangseon, Lim, Sangsoo, Nahmgoong, Hahn, Ji, Yul, Huh, Jin Young, Alfadda, Assim A., Kim, Sun, Kim, Jae Bum
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980432/
https://ncbi.nlm.nih.gov/pubmed/33836591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021073118
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