DNMT1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondrial dynamics

White adipose tissue (WAT) is a key regulator of systemic energy metabolism, and impaired WAT plasticity characterized by enlargement of preexisting adipocytes associates with WAT dysfunction, obesity, and metabolic complications. However, the mechanisms that retain proper adipose tissue plasticity...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Park, Yoon Jeong, Lee, Sangseon, Lim, Sangsoo, Nahmgoong, Hahn, Ji, Yul, Huh, Jin Young, Alfadda, Assim A., Kim, Sun, Kim, Jae Bum
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2021
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7980432/
https://ncbi.nlm.nih.gov/pubmed/33836591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021073118
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