Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease

Previously we have shown that a single dose of recombinant adenovirus serotype 26 (Ad26) vaccine expressing a prefusion stabilized SARS-CoV-2 spike antigen (Ad26.COV2.S) is immunogenic and provides protection in Syrian hamster and non-human primate SARS-CoV-2 infection models. Here, we investigated...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: van der Lubbe, Joan E. M., Rosendahl Huber, Sietske K., Vijayan, Aneesh, Dekking, Liesbeth, van Huizen, Ella, Vreugdenhil, Jessica, Choi, Ying, Baert, Miranda R. M., Feddes-de Boer, Karin, Izquierdo Gil, Ana, van Heerden, Marjolein, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., de Waal, Leon, Stittelaar, Koert J., Tolboom, Jeroen T. B. M., Serroyen, Jan, Muchene, Leacky, van der Fits, Leslie, Rutten, Lucy, Langedijk, Johannes P. M., Barouch, Dan H., Schuitemaker, Hanneke, Zahn, Roland C., Wegmann, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979827/
https://ncbi.nlm.nih.gov/pubmed/33741993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00301-y
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