Adenovector 26 encoded prefusion conformation stabilized RSV-F protein induces long-lasting Th1-biased immunity in neonatal mice

While RSV is a major cause of respiratory morbidity in infants, vaccine development is hindered by the immaturity and Th2-bias of the infant immune system and the legacy of enhanced respiratory disease (ERD) after RSV infection following immunization with formalin inactivated (FI)-RSV vaccine in ear...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: van der Fits, Leslie, Bolder, Renske, Heemskerk-van der Meer, Marjolein, Drijver, Joke, van Polanen, Yolinda, Serroyen, Jan, Langedijk, Johannes P. M., Schuitemaker, Hanneke, Saeland, Eirikur, Zahn, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293210/
https://ncbi.nlm.nih.gov/pubmed/32566260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0200-y
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