Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP

Safe and effective coronavirus disease–19 (COVID-19) vaccines are urgently needed to control the ongoing pandemic. While single-dose vaccine regimens would provide multiple advantages, two doses may improve the magnitude and durability of immunity and protective efficacy. We assessed one- and two-do...

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Publicado en:J Exp Med
Autores principales: Solforosi, Laura, Kuipers, Harmjan, Jongeneelen, Mandy, Rosendahl Huber, Sietske K., van der Lubbe, Joan E.M., Dekking, Liesbeth, Czapska-Casey, Dominika N., Izquierdo Gil, Ana, Baert, Miranda R.M., Drijver, Joke, Vaneman, Joost, van Huizen, Ella, Choi, Ying, Vreugdenhil, Jessica, Kroos, Sanne, de Wilde, Adriaan H., Kourkouta, Eleni, Custers, Jerome, van der Vlugt, Remko, Veldman, Daniel, Huizingh, Jeroen, Kaszas, Krisztian, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., Barouch, Dan H., Böszörményi, Kinga P., Stammes, Marieke A., Kondova, Ivanela, Verschoor, Ernst J., Verstrepen, Babs E., Koopman, Gerrit, Mooij, Petra, Bogers, Willy M.J.M., van Heerden, Marjolein, Muchene, Leacky, Tolboom, Jeroen T.B.M., Roozendaal, Ramon, Brandenburg, Boerries, Schuitemaker, Hanneke, Wegmann, Frank, Zahn, Roland C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Rockefeller University Press 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085771/
https://ncbi.nlm.nih.gov/pubmed/33909009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20202756
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