Cooperation between oncogenic Ras and wild-type p53 stimulates STAT non-cell autonomously to promote tumor radioresistance

Oncogenic RAS mutations are associated with tumor resistance to radiation therapy. Cell-cell interactions in the tumor microenvironment (TME) profoundly influence therapy outcomes. However, the nature of these interactions and their role in Ras tumor radioresistance remain unclear. Here we use Droso...

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Pubblicato in:Commun Biol
Autori principali: Dong, Yong-Li, Vadla, Gangadhara P., Lu, Jin-Yu (Jim), Ahmad, Vakil, Klein, Thomas J., Liu, Lu-Fang, Glazer, Peter M., Xu, Tian, Chabu, Chiswili-Yves
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979758/
https://ncbi.nlm.nih.gov/pubmed/33742110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01898-5
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