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Oncogenic Ras stimulates Eiger/TNF exocytosis to promote growth

Oncogenic mutations in Ras deregulate cell death and proliferation to cause cancer in a significant number of patients. Although normal Ras signaling during development has been well elucidated in multiple organisms, it is less clear how oncogenic Ras exerts its effects. Furthermore, cancers with on...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Chabu, Chiswili, Xu, Tian
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299269/
https://ncbi.nlm.nih.gov/pubmed/25411211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108092
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