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PP6 Disruption Synergizes with Oncogenic Ras to Promote JNK-dependent Tumor Growth and Invasion
RAS genes are frequently mutated in cancers, yet an effective treatment has not been developed. This is partly due to an incomplete understanding of signaling within Ras-related tumors. To address this, we performed a genetic screen in Drosophila, aiming to find mutations that cooperate with oncogen...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5580353/ https://ncbi.nlm.nih.gov/pubmed/28658615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.092 |
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