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THE NOVEL TUMOR SUPPRESSOR AND POLARITY GENE TRIM62 (DEAR1) SYNERGIZES WITH ONCOGENIC RAS IN INVASIVE LUNG CANCER
Deregulation of cell polarity proteins has been linked to the processes of invasion and metastasis. TRIM62, is a regulator of cell polarity and a tumor suppressor in breast cancer. Here, we demonstrate that human non-small cell lung cancer lesions show a step-wise loss of TRIM62 levels during diseas...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138305/ https://ncbi.nlm.nih.gov/pubmed/24890125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4385 |
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