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PP6 Disruption Synergizes with Oncogenic Ras to Promote JNK-dependent Tumor Growth and Invasion
RAS genes are frequently mutated in cancers, yet an effective treatment has not been developed. This is partly due to an incomplete understanding of signaling within Ras-related tumors. To address this, we performed a genetic screen in Drosophila, aiming to find mutations that cooperate with oncogen...
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| Опубликовано в: : | Cell Rep |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5580353/ https://ncbi.nlm.nih.gov/pubmed/28658615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.092 |
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