HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner

Uncovering the mechanisms that underpin how tumor cells adapt to microenvironmental stress is essential to better understand cancer progression. The HACE1 (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase) gene is a tumor suppressor that inhibits the growth, invasive capacity, a...

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Detaylı Bibliyografya
Yayımlandı:Oncogene
Asıl Yazarlar: Turgu, Busra, Zhang, Fan, El-Naggar, Amal, Negri, Gian Luca, Kogler, Melanie, Tortola, Luigi, Johnson, Fraser, Ng, Tony, Li, Amy, Yapp, Donald, Lockwood, William, Martinez, Daniel, Maris, John M., Daugaard, Mads, Penninger, Josef M., Hughes, Christopher S., Sorensen, Poul H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7979542/
https://ncbi.nlm.nih.gov/pubmed/33603169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01680-1
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