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HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner
Uncovering the mechanisms that underpin how tumor cells adapt to microenvironmental stress is essential to better understand cancer progression. The HACE1 (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase) gene is a tumor suppressor that inhibits the growth, invasive capacity, a...
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| 出版年: | Oncogene |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7979542/ https://ncbi.nlm.nih.gov/pubmed/33603169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01680-1 |
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