PTEN-mediated AKT/β-catenin signaling enhances the proliferation and expansion of Lgr5+ hepatocytes

Rationale: Compelling evidence suggests that Lgr5+ hepatocytes repair liver damage by promoting the regeneration of hepatocytes and ductal cells in the case of liver injury. The PTEN-mediated AKT/β-catenin signaling plays a key role in the regulation of innate immune regulation in the liver. However...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Sci
Hauptverfasser: Han, Jimin, Lin, Kaijun, Zhang, Xuezheng, Yan, Lingchen, Liu, Jianjun, Liu, Jia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2021
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7975694/
https://ncbi.nlm.nih.gov/pubmed/33767594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.56091
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