Fibroblast Growth Factor signaling regulates the expansion of A6-expressing hepatocytes in association with AKT-dependent β-catenin activation

BACKGROUND & AIMS: Fibroblast Growth Factors (FGFs) promote the proliferation and survival of hepatic progenitor cells (HPCs) via AKT-dependent β-catenin activation. Moreover, the emergence of hepatocytes expressing the HPC marker A6 during 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC)-induced...

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Main Authors: Utley, Sarah, James, David, Mavila, Nirmala, Nguyen, Marie V., Vendryes, Christopher, Salisbury, S. Michael, Phan, Jennifer, Wang, Kasper S.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995894/
https://ncbi.nlm.nih.gov/pubmed/24365171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.12.017
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