A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking

Polarization of node cells along the anterior-posterior axis of mouse embryos is responsible for left-right symmetry breaking. How node cells become polarized has remained unknown, however. Wnt5a and Wnt5b are expressed posteriorly relative to the node, whereas genes for Sfrp inhibitors of Wnt signa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dev Cell
Prif Awduron: Minegishi, Katsura, Hashimoto, Masakazu, Ajima, Rieko, Takaoka, Katsuyoshi, Shinohara, Kyosuke, Ikawa, Yayoi, Nishimura, Hiromi, McMahon, Andrew P., Willert, Karl, Okada, Yasushi, Sasaki, Hiroshi, Shi, Dongbo, Fujimori, Toshihiko, Ohtsuka, Toshihisa, Igarashi, Yasunobu, Yamaguchi, Terry P., Shimono, Akihiko, Shiratori, Hidetaka, Hamada, Hiroshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7974384/
https://ncbi.nlm.nih.gov/pubmed/28292423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.02.010
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg